Rise to Fame
The State ran on MTV from 1993-1995 and got canceled before most of its fans could drive. Lo Truglio was in it, along with the people who would go on to make Reno 911!, Wet Hot American Summer, and Wanderlust. He spent the next decade in supporting roles across the Judd Apatow circuit, the kind of face you recognized from Superbad or Role Models without knowing his name. Brooklyn Nine-Nine gave him the role that stuck: Charles Boyle, Jake Peralta's best friend and perennial also-ran. Lo Truglio played him as someone genuinely incapable of bitterness, which is harder than it looks.
In the Spotlight
Brooklyn Nine-Nine ended in 2021 with eight seasons and no public disasters, which is a better exit than most ensemble comedies get. The show moved from Fox to NBC mid-run and kept its audience anyway, something almost no network comedy does. He made his directorial debut with Outpost in 2022, a horror film starring his wife Beth Dover. The Charles Boyle character looked easy while the show was running. It wasn't, and streaming has made that clearer.
Side Notes
He grew up in Margate, Florida, shooting horror films on Super 8 and collecting Mad magazines before he had a career plan. At NYU he fell in with the group that became The State, the MTV sketch comedy that produced Thomas Lennon, Ken Marino, Michael Ian Black, and David Wain. Most of them have been in each other's projects ever since: Wet Hot American Summer, Reno 911!, Wanderlust. He married actress Beth Dover in 2014 and has cast her in multiple projects since. Whether that's romantic or efficient probably depends on who you ask.