She came through the Guildhall School of Music and Drama and landed at Shakespeare's Globe before most young actors have their first screen credit. Her nomination for Best Actress at the Stage Debut Awards came from Much Ado About Nothing in 2017. A year later she was in Wanderlust on BBC. By 2019, she was Yennefer of Vengerberg in Netflix's The Witcher, a character built on grief and ambition rather than standard fantasy love interest beats. The show hit big. She won the IMDb Breakout STARmeter Award in 2020.
The Witcher has one season left, and Chalotra is the one cast member who made it through the franchise's biggest shake-up without her own standing taking a hit. Henry Cavill left after season 3, Liam Hemsworth replaced him for season 4, and she stayed Yennefer through all of it. Season 4 arrived in October 2025. Beyond the franchise, her satirical thriller Two Neighbors premiered at the Edinburgh International Film Festival in 2025. She's already writing what comes next.
Her father is Kashmiri and her mother is English, and she grew up in Wolverhampton watching Bollywood films as her dad's way of passing on his culture. She traveled to India for the first time in 2019, going to Pathankot in Punjab with her father to meet his family. She has said she started taking Hindi classes to stay more connected to that side of her heritage. Her brother Arun also acts, and she produced the short drama Queens with him and her boyfriend Josh Dylan. The formal Guildhall training and the Bollywood childhood are not as far apart as they sound.